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Sweet success - making a bitter pill easier to swallow 01 January 0001 Researchers from Perth Children’s Hospital (PCH) and The University of Western Australia (UWA) have successfully trialled a new approach to the problem of convincing reluctant young patients to swallow bitter-tasting medication before their surgery. The team conducted a clinical trial over a 28-month period to assess the taste, tolerability and absorption rates of the chocolate-tasting, chewable tramadol compared to an oral liquid formulation based on tramadol capsules. Tramadol is an opioid pain medication that can be prescribed to treat postoperative pain in children. The children who participated in the trial were given the novel chewable tramadol tablet or oral tramadol liquid before anaesthetic was administered. Led by PCH Consultant Paediatric Anaesthetist and Chair of Paediatric Anaesthesia at UWA Professor Britta von Ungern-Sternberg and UWA Professor of Pharmaceutics Lee Y...
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Premmies to test power of probiotics 01 January 0001 Some of Western Australia’s tiniest babies are helping to test the gut-boosting potency of probiotics, as part of exciting new research that will determine whether increasing supplementation enhances their gut health, thereby reducing their risk of serious health complications. A 2023 Telethon Trust Research Fellowship is enabling King Edward Memorial Hospital neonatal registrar Dr Chandra Rath to lead the project which could change the lives of the more than 500 Western Australians born at less than 32 weeks’ gestation every year. ‘These babies are our most vulnerable patients,’ he explains. ‘They are at high risk of poor nutrition, leaving them susceptible to a host of serious – and potentially life-threatening – health conditions such as late-onset sepsis and a devastating intestinal disease (necrotising enterocolitis) to which an imbalance of...
Last Updated:
22/06/2021